IGF-1 LR3 Peptide — Long Arginine Insulin-Like Growth Factor | Research Grade
IGF-1 LR3 is an 83-amino-acid research peptide analog of insulin-like growth factor-1, carrying a Long Arg3 modification that reduces IGFBP binding affinity. Supplied as a lyophilized vial for in-vitro laboratory research use only.
- CAS Number: 946870-92-4
- Sequence length: 83 amino acids · Half-life: ~20-30 hours (literature-reported)
- Purity: ≥99% HPLC, third-party tested, COA included
- Shipping: USA same-day (before 2pm CT M-F) · free over $200
Related: Sermorelin · CJC-1295 + Ipamorelin
For laboratory research use only. Not for human or animal consumption. Full details ↓
Original price was: $ 90.00.$ 70.00Current price is: $ 70.00.
In stock
| Quantity | Price | Discount |
|---|---|---|
| 3-5 | $ 63.00 | 10% |
| 6-9 | $ 59.50 | 15% |
| 10+ | $ 56.00 | 20% |
In stock
Description
IGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1) is an 83-amino-acid research peptide, a modified analog of IGF-1. LiveWell supplies it as a lyophilized vial strictly for in-vitro laboratory research use only.
Structure
An arginine substitution at position 3 and a 13-amino-acid N-terminal extension distinguish IGF-1 LR3 from native IGF-1. These modifications reduce binding affinity to IGF-binding proteins (IGFBPs), the property most often examined in comparative research.
Chemical information
- CAS Number: 946870-92-4
- Sequence length: 83 amino acids
- Class: IGF-1 analog (Long Arg3 variant)
- Half-life: ~20–30 hours reported in published literature (vs ~10 minutes for native IGF-1)
Studied in
- IGF-1 signalling and IGF-1R receptor research
- IGFBP interaction and binding-affinity studies
- Protein folding, disulfide structure and conformational analysis
- Comparative insulin / IGF-1 receptor research
Storage & handling
- Store refrigerated at 2–8°C, protected from light and heat
- Reconstitute with bacteriostatic water; reconstituted material has a shorter storage window
⚠️ Disclaimer: IGF-1 LR3 is intended strictly for laboratory research and in-vitro use only. Not for human or animal use. No therapeutic, performance, or physique claims are made or implied.
Buy IGF-1 LR3 — cGMP Manufactured in Dallas, TX
LiveWell manufactures research-grade IGF-1 LR3 in our cGMP facility in Dallas, Texas. Every vial is third-party tested to ≥99% HPLC purity, with COA published on our COA page. US orders before 2pm CT (Mon–Fri) ship same-day, free shipping over $200.
Related research compounds
Sermorelin · CJC-1295 + Ipamorelin · Tesamorelin/Ipamorelin Blend · Bacteriostatic Water · Certificates of Analysis
Research literature
IGF-1 Long Arg3 has been the subject of 16 peer-reviewed publications indexed in PubMed. Selected recent literature for research reference:
- Li X et al. (2004). Integration of hydrogen/deuterium exchange and cyanylation-based methodology for conformational studies of cystinyl proteins. Anal Biochem. PMID: 15246005
- Shoubridge CA et al. (2003). Preferential intestinal delivery of long[Arg3] insulin-like growth factor (LR3IGF-I) over IGF-I in preweaning and adult rats. Endocrinology. PMID: 12697696
- Khamsi F et al. (2001). Differential effects of insulin-like growth factor-I and gonadotropins on the proliferative activity of two subgroups of granulosa cells: cumulus oophorus and mural granulosa cells. Fertil Steril. PMID: 11334915
- Laajoki LG et al. (2000). Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I. J Biol Chem. PMID: 10744677
- Yang Y et al. (1999). Probing the folding pathways of long R(3) insulin-like growth factor-I (LR(3)IGF-I) and IGF-I via capture and identification of disulfide intermediates by cyanylation methodology and mass spectrometry. J Biol Chem. PMID: 10608814
References are provided for research reference only. Inclusion of literature does not constitute a recommendation, endorsement, or claim for any specific use of LiveWell Peptides products. Products are sold for laboratory and research use only and are not intended for human consumption, injection, topical application, or any other administration to the human body.
Frequently Asked Questions
What is IGF-1 LR3?
An 83-amino-acid analog of IGF-1 (CAS 946870-92-4) with a Long Arg3 modification reducing IGFBP binding affinity. Supplied as a lyophilized vial for laboratory research use only.
How does IGF-1 LR3 differ from native IGF-1?
The Arg3 substitution and N-terminal extension reduce IGFBP binding affinity and extend the reported half-life to ~20-30 hours, compared to ~10 minutes for native IGF-1 — the properties most examined in comparative research.
What purity is LiveWell IGF-1 LR3, and is a COA included?
Every batch is third-party tested at ≥99% HPLC purity, with a Certificate of Analysis published on our COA page.
How should IGF-1 LR3 be stored?
Store refrigerated at 2–8°C, protected from light and heat. Reconstitute with bacteriostatic water; use within a shorter window after reconstitution.
Is this product for human use?
No. Sold strictly for laboratory research use only. Not FDA approved, not for human or veterinary consumption.
Research Use Only. No therapeutic or performance claims are made or implied.
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