Dihexa — 10mg Tablets (60ct)
Dihexa (PNB-0408) is a blood-brain-barrier-penetrant oligopeptide analog of Angiotensin IV, characterized as a positive allosteric modulator of HGF/c-Met receptor signalling. Supplied as a 10mg research tablet, 60 tablets per bottle, for in-vitro laboratory research use only.
- CAS 1401708-83-5 · molecular weight ≈504.67 g/mol (C27H44N4O5)
- 10mg per tablet · 60 tablets per bottle
- 99%+ purity, HPLC-verified · batch-specific Certificate of Analysis
- Ships from Dallas, TX · same-day dispatch on orders before 2pm CT (M–F)
Related research: AOD-9604 · NAD+ · All research tablets
For laboratory research use only — not for human or veterinary use. Full research details below.
$ 129.99
In stock
| Quantity | Price | Discount |
|---|---|---|
| 3-5 | $ 116.99 | 10% |
| 6-9 | $ 110.49 | 15% |
| 10+ | $ 103.99 | 20% |
In stock
Description
Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, developmental code PNB-0408) is a blood-brain-barrier-penetrant oligopeptide analog derived from Angiotensin IV, originally engineered by Joseph W. Harding and John W. Wright at Washington State University. LiveWell Peptides supplies it as a 10mg research tablet, 60 tablets per bottle, strictly for in-vitro laboratory research.
Mechanism studied & structure
Dihexa is characterised in the published literature as a high-affinity positive allosteric modulator of hepatocyte growth factor (HGF) that potentiates c-Met receptor signalling. This HGF/c-Met interaction is the property examined in dendritic spinogenesis and synaptic-connectivity research using neuronal models, and is what structurally distinguishes the compound from unmodified Angiotensin IV. It is supplied as a reference material for receptor- and pathway-level laboratory study only.
Chemical information
- Name: Dihexa
- CAS Number: 1401708-83-5
- Also known as: PNB-0408, ATH-1001, Hexanoyl-Tyr-Ile-Ahx-NH2, N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide
- Sequence: Hexanoyl-Tyr-Ile-Ahx-NH2
- Type: Synthetic oligopeptide (Angiotensin IV analog)
- Molecular formula: C27H44N4O5
- Molecular weight: ≈504.67 g/mol
Studied applications
- HGF/c-Met receptor signalling research
- Dendritic spinogenesis and synaptic connectivity studies in neuronal models
- Comparative research against native Angiotensin IV
- PI3K/AKT-associated pathway research
Solubility & handling note
Published vendor datasheets report that Dihexa is soluble in DMSO (brief ultrasonic treatment assists dissolution) and only slightly soluble in aqueous media, so DMSO or an equivalent organic solvent is typically selected for stock preparation. Adding water to a DMSO stock may cause cloudiness. Allow both the material and the chosen solvent to reach ambient laboratory temperature before preparation. Confirm target stock concentration against the batch Certificate of Analysis.
Storage & handling
- Store the sealed bottle at controlled room temperature (15–25°C), away from light, heat and moisture
- For extended archiving, refrigerated (2–8°C) or frozen (−20°C) storage is used in the literature
- Keep the desiccant in the bottle and reseal after each access
- Handle only by qualified personnel in an appropriate laboratory setting; follow your laboratory’s standard handling and disposal protocol
Buy Dihexa — cGMP Manufactured in Dallas, TX
LiveWell Peptides manufactures Dihexa under cGMP processes at our facility in Dallas, Texas (USA). US orders placed before 2pm CT (Mon–Fri) ship same-day, with free domestic shipping on orders over $200. Bulk and wholesale pricing is available — contact our sales team.
Why Researchers Source Dihexa from LiveWell
- Documentation, not claims: every batch ships with a batch-specific Certificate of Analysis documenting identity and purity.
- Four-point testing: identity and purity verified by HPLC and mass spectrometry to a 99%+ specification.
- Cold-chain logistics: temperature-appropriate handling and packaging from our Dallas facility.
- Bulk pricing: automatic volume discounts and dedicated wholesale support.
Related research compounds
AOD-9604 · NAD+ · All research tablets · Certificates of Analysis
Frequently Asked Questions
What is Dihexa?
Dihexa (PNB-0408) is a synthetic oligopeptide analog of Angiotensin IV, supplied as a research-grade reference material in tablet form for in-vitro laboratory study of HGF/c-Met receptor signalling. It is not for human or veterinary use.
What is the chemical makeup of Dihexa?
Dihexa (Hexanoyl-Tyr-Ile-Ahx-NH2), CAS 1401708-83-5, has the molecular formula C27H44N4O5 and a molecular weight of approximately 504.67 g/mol. Full chemical documentation is included with each Certificate of Analysis.
How does Dihexa differ from native Angiotensin IV?
Dihexa is a metabolically-stabilised structural analog of Angiotensin IV. In laboratory research it is characterised as a positive allosteric modulator of HGF/c-Met signalling, and its terminal modifications are studied for improved stability and membrane permeability relative to the unmodified parent peptide.
What is the purity, and is a Certificate of Analysis included?
Each batch is 99%+ pure, HPLC-verified, and accompanied by a batch-specific Certificate of Analysis documenting identity and purity, published on our COA page.
How much material is in each unit?
Each tablet contains 10mg of Dihexa, with 60 tablets per bottle.
How should this material be stored?
Store the sealed bottle at controlled room temperature (15–25°C), away from light, heat and moisture, keeping the desiccant in place. Refrigerated or frozen storage is used for extended archiving. Handle only by qualified personnel in an appropriate laboratory setting.
Is this product intended for human use?
No. This product is strictly for laboratory, research and educational purposes only. It is not for human or veterinary consumption and must never be ingested.
Where does it ship from?
Orders ship from our facility in Dallas, Texas. US orders placed before 2pm CT (Mon–Fri) ship same-day, with free domestic shipping on orders over $200.
Resumen (ES): Dihexa (PNB-0408) es un análogo oligopeptídico de la Angiotensina IV, suministrado como comprimido de investigación de 10mg (60 por frasco) únicamente para uso de investigación de laboratorio in-vitro.
Disclaimer: This product is not a drug, dietary supplement, or food product. It has not been evaluated or approved by the FDA. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease, and is not intended for ingestion by humans or animals. No therapeutic or cognitive-enhancement claims are made or implied. For in-vitro laboratory research use only.
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