Orforglipron — 6mg Tablets (90ct)
Orforglipron is an orally bioavailable, non-peptide small-molecule GLP-1 receptor agonist, studied for receptor-binding kinetics at the GLP-1 receptor. Supplied as a 6mg research tablet, 90 tablets per bottle, for laboratory research use only.
- CAS Number: 2212020-52-3
- Type: Non-peptide small molecule (not a peptide)
- Purity: 99% HPLC-verified, COA included
- Shipping: USA same-day (before 2pm CT M-F) · free over $200
For laboratory research use only. Not for human or animal consumption. Full details ↓
$ 199.99
Only 3 left in stock
| Quantity | Price | Discount |
|---|---|---|
| 3-5 | $ 179.99 | 10% |
| 6-9 | $ 169.99 | 15% |
| 10+ | $ 159.99 | 20% |
Only 3 left in stock
Description
Orforglipron (development code LY3502970) is an orally bioavailable, non-peptide small-molecule GLP-1 receptor agonist. Unlike peptide-based GLP-1 receptor agonists, it lacks peptide bonds entirely, which is studied for its resistance to protease degradation (e.g. DPP-4). Supplied as a 6mg research tablet, 90 tablets per bottle, strictly for in-vitro laboratory research.
Mechanism studied
Orforglipron is characterised in the literature as an agonist at the GLP-1 receptor (GLP-1R), a class B G protein-coupled receptor. It is studied for its receptor-binding kinetics, cAMP-pathway activation, and structural differences from peptide-based GLP-1R agonists — being a fundamentally different chemical scaffold designed to engage the receptor’s orthosteric binding pocket without a peptide backbone.
Chemical information
- Name: Orforglipron (LY3502970)
- CAS Number: 2212020-52-3
- Type: Non-peptide small-molecule GLP-1 receptor agonist
Studied in
- GLP-1 receptor (GLP-1R) binding and signalling research
- cAMP-pathway activation studies in cell-based assays
- Comparative research against peptide-based GLP-1R agonists
- Structure-activity research on non-peptide GPCR ligands
Storage & handling
- Store the sealed bottle at controlled room temperature, away from light, heat and moisture
- Keep the desiccant in the bottle and reseal after each access
- Handle only by qualified personnel in an appropriate laboratory setting
Related research compounds
Semaglutide · Tirzepatide · Certificates of Analysis
Frequently Asked Questions
What is Orforglipron?
Orforglipron (CAS 2212020-52-3) is a non-peptide small-molecule GLP-1 receptor agonist. Supplied as a research tablet strictly for laboratory research use only. It is not an FDA-approved product.
How does Orforglipron differ from peptide-based GLP-1 agonists?
Orforglipron is a synthetic non-peptide molecule that lacks peptide bonds entirely, distinguishing it structurally from peptide-based GLP-1 receptor agonists such as Semaglutide. This structural difference is studied for its effect on protease resistance and receptor-binding characteristics.
What purity is included, and is a COA available?
Each batch is 99%+ pure, HPLC-verified, with a batch-specific Certificate of Analysis published on our COA page.
How should this material be stored?
Store at room temperature, away from light, heat and moisture, keeping the desiccant in place. Handle only by qualified personnel in an appropriate laboratory setting.
Is this product intended for human use?
No. Orforglipron is not FDA-approved and this material is sold strictly for laboratory research use only. Not for human or veterinary consumption.
Research Use Only. This product is not the investigational drug product under clinical development by any pharmaceutical company. No therapeutic, weight-management or metabolic-health claims are made or implied.
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