GHK-CU

GHK-Cu is a copper-binding tripeptide (Gly-His-Lys) that occurs naturally in human plasma and is studied for its role in tissue regeneration, skin remodeling, and antioxidant signaling.

Research-grade specs

• Sequence: Gly-His-Lys + Cu²⁺
• Length: 3 amino acids
• Discovery: 1973, in human plasma
• Half-life: Hours systemically

Studied applications

• Skin remodeling research — collagen and elastin synthesis modulation
• Hair follicle research — promoter of follicular vascularization in animal models
• Wound-healing research — accelerated closure and reduced inflammation
• Anti-inflammatory and antioxidant signaling pathway studies

Quality & trust

• ≥99% HPLC purity, third-party tested
• Mass spectrometry identity confirmation
• LAL endotoxin testing on every batch
• Batch-specific Certificate of Analysis included
• USA same-day shipping (orders before 2pm CT M-F)

Related research: KLOW peptide blend

Research literature

GHK-Cu has been the subject of 165 peer-reviewed publications indexed in PubMed. Selected recent literature for research reference:

• Skurski P et al. (2026). Carbonless amino acids and a carbonless GHK peptide. Phys Chem Chem Phys. PMID: 41859865
• Hu J et al. (2026). Glycyl-L-histidyl-L-lysine-Cu2(+) (GHK-Cu) Attenuates CuSO(4) or LPS induced-inflammation in Zebrafish larvae model. Eur J Pharmacol. PMID: 41997403
• Mendias CL et al. (2026). Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance. Sports Med. PMID: 41966639
• Wang R et al. (2026). Golgi-targeted copper delivery strategy via enhancing copper-dependent proteins’ activity for fascia regeneration. J Control Release. PMID: 41371501
• Rahman OF et al. (2026). Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. J Am Acad Orthop Surg Glob Res Rev. PMID: 41490200

References are provided for research reference only. Inclusion of literature does not constitute a recommendation, endorsement, or claim for any specific use of LiveWell Peptides products. Products are sold for laboratory and research use only and are not intended for human consumption, injection, topical application, or any other administration to the human body.