Not for human consumption

GHRP-2 Peptide (Pralmorelin): GH Secretagogue Hexapeptide | Research Grade

GHRP-2 research peptide: ≥99% HPLC-verified purity, manufactured in LiveWell’s own Dallas cGMP facility. GHRP-2 (pralmorelin, KP-102) is a synthetic hexapeptide GH secretagogue and the only GHRP with a regulatory approval anywhere: in Japan it is an approved diagnostic agent for growth hormone deficiency testing. Supplied as a 10 mg lyophilized vial for in-vitro laboratory research use only.

Coming soon: pre-orders are open now. The first production batch is in the manufacturing and QC queue. Expected ship date: to be announced. Pre-orders ship in the order received once the batch clears third-party testing and the COA is published. Your card is charged at checkout and you can cancel any time before shipment for a full refund.

CAS Number: 158861-67-7 · Also known as: pralmorelin, KP-102, GPA-748
Vial size: 10 mg lyophilized powder
Class: Growth hormone secretagogue (GHRP family), GHS-R1a agonist
Purity: ≥99% HPLC, third-party tested, COA published on release
Shipping: USA same-day once released (orders before 2pm CT, Mon to Fri) · free over $200

Related: Ipamorelin · Sermorelin · CJC-1295 + Ipamorelin

For laboratory research use only. Not for human or animal consumption. Full details ↓

$ 39.99

Available on backorder

⚠️ Strictly for laboratory research use only. Not for human or animal consumption.

Quantity	Price	Discount
3-5	$ 35.99	10%
6-9	$ 33.99	15%
10+	$ 31.99	20%

Available on backorder

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Description

GHRP-2 (Pralmorelin): GH Secretagogue for Research Use

GHRP-2 (pralmorelin, KP-102, D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2) is a synthetic six-amino-acid growth hormone secretagogue acting as an agonist of the ghrelin receptor GHS-R1a at both the hypothalamus and the pituitary. It holds a unique position in the GHRP family: in Japan, pralmorelin hydrochloride is an approved diagnostic agent, used as a stimulation test for adult and childhood growth hormone deficiency with a defined peak-GH cut-off. That regulatory history gives GHRP-2 one of the richest clinical-endocrinology literatures of any research secretagogue. LiveWell supplies it as a 10 mg lyophilized vial strictly for in-vitro laboratory research use only.

Chemical Information

Name: GHRP-2 (pralmorelin, KP-102, GPA-748)
CAS Number: 158861-67-7
Type: Synthetic hexapeptide GH secretagogue (research grade)
Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Molecular weight: approximately 817 g/mol
Mechanism: GHS-R1a agonist at hypothalamus and pituitary; also stimulates ACTH and cortisol release in published testing
Vial size: 10 mg lyophilized powder
Purity: ≥99% (HPLC, third-party tested)

Why Researchers Study GHRP-2

1. The only approved GHRP. Pralmorelin’s diagnostic approval in Japan produced standardized human stimulation-test data: the severe adult GH deficiency cut-off is a peak GH of 9 ng/mL or lower on the GHRP-2 test.

2. Pituitary axis research. The 2022 J Endocr Soc series reported that the ACTH response during a GHRP-2 test screens for secondary adrenal insufficiency with 83% sensitivity and 88% specificity, extending the compound beyond the GH axis.

3. GHRH-independent GH release. Long-term GHRP-2 treatment in the GHRH knockout mouse demonstrated GH stimulation independent of GHRH, a foundational result for the two-receptor model of GH regulation studied with CJC-1295 with DAC and Sermorelin on the GHRH side.

4. Comparative secretagogue research. GHRP-2 sits between GHRP-6 (the founding compound) and Hexarelin (the most potent) in the classic hexapeptide series, making the three a standard panel in GHS-R1a assays.

Published Clinical Literature (Research Reference)

For context only. These are findings from the Japanese clinical endocrinology literature and academic laboratories. These are results cited from peer-reviewed sources; they are not claims about LiveWell’s research-grade material.

GHRH knockout mouse (Am J Physiol Endocrinol Metab, 2005): long-term GHRP-2 stimulated GH independent of GHRH signaling.
Diagnostic test review (Eur J Endocrinol, 2007): evaluates the GHRP-2 test as a candidate standard for GH deficiency testing.
Pediatric series (J Pediatr Endocrinol Metab, 2010): median peak GH 3.39 vs 25.10 mcg/L in GH-deficient versus non-deficient children, with a sensitivity-specificity crossover near 15 mcg/L.
Preoperative pituitary series (Endocr J, 2020): GHRP-2 peak GH values reflected hypopituitarism severity and predicted postoperative recovery in non-functioning pituitary adenomas.
Adrenal screening (J Endocr Soc, 2022): an ACTH response of 1.55-fold or greater during the GHRP-2 test screened for secondary adrenal insufficiency with 83% sensitivity and 88% specificity.
Regulatory: approved in Japan as pralmorelin hydrochloride for diagnostic GH stimulation testing; not approved in the US or EU; prohibited in sport by WADA.

Storage & Handling

Store lyophilized vials refrigerated at 2 to 8°C, protected from light and heat
Reconstitute with bacteriostatic water; reconstituted material has a shorter storage window
Follow your laboratory’s standard peptide handling protocol

⚠️ Disclaimer: GHRP-2 research peptide is intended strictly for laboratory research and in-vitro use only. It is not a drug, food, cosmetic, or dietary supplement. This product has not been evaluated or approved by the FDA and is not for human or veterinary use. No therapeutic, weight-management or metabolic-health claims are made or implied.

Regulatory status: Pralmorelin (GHRP-2) is approved in Japan only as a diagnostic agent for growth hormone deficiency testing. It has no therapeutic approval anywhere, is not approved in the United States or the European Union, and is listed on the WADA prohibited list. The research-grade material sold by LiveWell is not a drug product: it is not manufactured, compounded, or approved for pharmaceutical use, and is strictly for in-vitro laboratory research. Nothing on this page constitutes medical advice.

GHRP-2 research reference: View the GHRP-2 test series on PubMed

Pre-Order GHRP-2 Research Peptide: cGMP Manufactured in Dallas, TX

Qualified researchers can pre-order GHRP-2 directly from the manufacturer. LiveWell Peptides produces research-grade GHRP-2 in our cGMP facility in Dallas, Texas. Every vial is third-party tested to verify ≥99% HPLC purity, amino acid identity by mass spectrometry, and endotoxin limits by LAL testing, and the batch COA is published on our COA page on the day of release. Pre-orders ship in the order received (expected ship date: to be announced); once released, US orders placed before 2pm CT (Mon to Fri) ship same-day in cold-chain packaging, with free domestic shipping over $200. International shipping is available.

Why Researchers Source GHRP-2 from LiveWell

Documentation, not claims. Every batch ships with a verified COA confirming identity and purity, published on our COA page rather than supplied only on request.

Four-point analytical testing. HPLC for purity, mass spectrometry for amino acid identity, and LAL testing for endotoxins, with independent third-party verification on top of in-house quality control.

US manufacturing and cold-chain logistics. Orders ship from our Dallas, Texas facility, with international shipping to Colombia, Mexico, Brazil, Argentina, Chile and Peru.

Related research compounds

Hexarelin (GHS-R1a + CD36) · GHRP-6 · Ipamorelin (selective GHS-R agonist) · Sermorelin (GHRH 1-29) · Bacteriostatic Water · Certificates of Analysis

Research literature

Selected peer-reviewed sources for research reference:

Alba M et al. (2005). Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. PMID: 15985453
Brabant G et al. (2007). GH releasing peptide 2 test: the holy grail of testing GH deficiency? Eur J Endocrinol. PMID: 17609398
Asakura Y et al. (2010). Growth hormone response to GH-releasing peptide-2 in children. J Pediatr Endocrinol Metab. PMID: 20662346
Soga A et al. (2020). Preoperative growth hormone peak values during a GH releasing peptide-2 test reflect the severity of hypopituitarism in patients with non-functioning pituitary adenomas. Endocr J. PMID: 31776295
Suzuki S et al. (2022). Clinical Usefulness of the Growth Hormone-Releasing Peptide-2 Test for Hypothalamic-Pituitary Disorder. J Endocr Soc. PMID: 35795807

References are provided for research reference only. Inclusion of literature does not constitute a recommendation, endorsement, or claim for any specific use of LiveWell Peptides products. Products are sold for laboratory and research use only and are not intended for human consumption, injection, topical application, or any other administration to the human body.

Frequently Asked Questions

What is GHRP-2?

GHRP-2 (pralmorelin, KP-102, CAS 158861-67-7) is a synthetic hexapeptide agonist of the ghrelin receptor GHS-R1a, and the only GHRP with a regulatory approval anywhere: a diagnostic approval in Japan for GH deficiency testing. We supply it as a 10 mg lyophilized vial strictly for in-vitro laboratory research.

Is GHRP-2 approved anywhere?

Yes, in Japan, where pralmorelin hydrochloride is approved as a growth hormone stimulation test agent for diagnosing GH deficiency. It has no therapeutic approval in any country and is not approved in the US or EU.

How does GHRP-2 differ from GHRP-6 and Hexarelin?

All three are GHS-R1a hexapeptides. GHRP-6 is the founding compound of the family, Hexarelin is the most potent GH releaser and adds CD36 binding, and GHRP-2 is the one that reached regulatory approval as a diagnostic, giving it the largest standardized human dataset.

How does GHRP-2 differ from Ipamorelin?

Ipamorelin is noted in the literature for GH selectivity with minimal cortisol and prolactin response. GHRP-2 produces a stronger GH response but also stimulates ACTH and cortisol, a property the Japanese literature has turned into an adrenal screening application.

What is the GHRP-2 test cut-off?

In the Japanese diagnostic framework, a peak GH of 9 ng/mL or lower during the GHRP-2 test indicates severe adult growth hormone deficiency. Cited for research reference only.

What purity is LiveWell GHRP-2, and is a COA included?

Every batch is third-party tested at ≥99% purity by HPLC, with mass spectrometry identity confirmation and LAL endotoxin testing. The batch Certificate of Analysis is published on our COA page the day the pre-order batch is released.

How should GHRP-2 be stored and reconstituted?

Store the lyophilized vial refrigerated at 2 to 8°C, protected from light and heat. Reconstitute with bacteriostatic water; reconstituted material has a considerably shorter storage window.

How do pre-orders work, and when will it ship?

Pre-orders are charged at checkout and ship in the order received once the first batch clears third-party testing and the COA is published. You will receive tracking the day it ships. If you change your mind before shipment, contact us for a full refund.

Is GHRP-2 a drug or supplement in the United States?

No. In the United States GHRP-2 is not approved by the FDA for any use. The research-grade material sold by LiveWell is not a drug product, dietary supplement, food or cosmetic, and it is not intended for human or animal consumption.

Péptidos de investigación disponibles con envío internacional. GHRP-2 de grado de investigación fabricado en instalaciones cGMP en Dallas, Texas. Certificado de análisis incluido con cada lote. Solo para uso en investigación.

Research Use Only Disclaimer: This product is sold strictly for in vitro laboratory research. NOT for human or animal consumption. LiveWell Peptides makes no medical claims.