Semax

Semax is a 7-amino-acid synthetic analog of the ACTH(4-10) fragment with a Pro-Gly-Pro extension, developed in Russia and used in clinical practice there for stroke recovery — studied internationally as a nootropic peptide.

Research-grade specs

• Sequence length: 7 amino acids
• Class: ACTH(4-7) analog / nootropic
• Origin: Russian research, 1980s
• Administration in research: Intranasal common

Studied applications

• Cognitive performance research (focus, memory)
• Neuroprotection — used clinically in Russia for ischemic stroke recovery
• BDNF and NGF (nerve growth factor) modulation studies
• Comparative research vs Selank

Quality & trust

• ≥99% HPLC purity, third-party tested
• Mass spectrometry identity confirmation
• LAL endotoxin testing on every batch
• Batch-specific Certificate of Analysis included
• USA same-day shipping (orders before 2pm CT M-F)

Related research: Selank

Research literature

Semax has been the subject of 226 peer-reviewed publications indexed in PubMed. Selected recent literature for research reference:

• Rahman OF et al. (2026). Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. J Am Acad Orthop Surg Glob Res Rev. PMID: 41490200
• Giri S et al. (2025). Modulation of neuropathological pathways by bioactive peptides and proteins/polypeptides: Targeting oxidative stress in neurodegenerative diseases. Neuropeptides. PMID: 41004910
• Liu R et al. (2025). Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice. Br J Pharmacol. PMID: 40692165
• Radchenko AI et al. (2025). The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer’s Disease. Acta Naturae. PMID: 41479572
• Asadullah A et al. (2023). Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats). F1000Res. PMID: 41179234

References are provided for research reference only. Inclusion of literature does not constitute a recommendation, endorsement, or claim for any specific use of LiveWell Peptides products. Products are sold for laboratory and research use only and are not intended for human consumption, injection, topical application, or any other administration to the human body.